Before you shutdown your system be sure you close Chrome

The Fall Creators Update brought some considerable changes. These updates don’t radically change Windows 10, but they do make modifications around the operating system that you’ll notice.

One of these is Windows’s new ability to re-open programs after you reboot. In prior versions, Windows would start you with a blank slate (aside from startup programs). Now, Windows tries to open the apps you had running when you last shut down.

How to Stop Windows 10 From Reopening Last Open Apps on Startup

Press Windows key + D to hide all windows and show the desktop. Then, press Alt + F4 to show the shutdown dialog. Select Shut down from the list and click OK to confirm.

Note that even closing all the windows, there is still a Chrome process hanging in background for the Crashpad Handler. Given that it's started using the same executable file chrome.exe, it seems Windows is calling that executable after rebooting.

With your edit to autoruns, you probably disabled the background process for Crashpad Handler, so chrome.exe restarts only when there was some window opened before the boot.

This is a new feature/bug in the Fall upodate, a workaround is to turn off auto log in after a restart or update - Open Settings, and click/tap on the Accounts icon.
Click/tap on Sign-in options on the left side, and turn Off ‘Use my sign-in info to automatically finish setting up my device after an update or restart’.

Can also shutdown or restart after giving the desktop focus and using the key combo ALT+F4 to bring up the shutdown dialog. Then it shutdowns/restarts the old fashion way.

Make a desktop Shortcut will old fashion way too;

Shutdown /S /t 2

Shutdown /R /t 2

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